Researchers successfully eliminate HIV virus from cultured human cells
The HIV-1 virus has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.
”This is one important step on the path toward a permanent cure for AIDS,” said Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Dr. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. “It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction,” added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.
If you get sick with an infection, you usually take antibiotics, which (if they do what they’re supposed to do) make you better by killing bacteria. This medical treatment seems simple, but many nasty types of bacterial are growing increasingly resistant to antibiotics. A team of scientists at McMaster University in Canada have found a molecule in some soil-dwelling fungus that is capable of disarming some antibiotic resisting properties, making even stubborn bacterial infections treatable with standard antibiotics.
Antibiotic resistance has been a source of concern for doctors, particularly since we haven’t discovered any new antibiotics since the 1980s. Finding this new molecule, called AMA, in a certain fungus that grows in soil is way easier than trying to create new treatments for superbugs from scratch. The superbugs in question contain New Delhi Metallo-beta-Lactamase-1, or NDM-1, and are considered a global threat by the World Health Organization. AMA effectively wipes out NDM-1, which then allows antibiotics to do their work.
In their experiments, the researchers combined the NDM-1 gene with harmless E. coli bacteria, and then infected mice with this engineered superbug. One group of mice were given both AMA and an antibiotic, the second group were given just AMA, and the third were given just an antibiotic. Of the three groups, only the mice receiving the AMA plus the antibiotic survived.
The implications for this research are that we may soon have a new weapon in our fight against one of the most challenging health care problems of this decade. Antibiotic-resistant superbugs are spreading rapidly across the globe, killing indiscriminately, and we need to stop them before it’s too late. Or as soon as we get around to it, anyway.
Nicholas Lord, a Navy sailor since 2008 currently on active duty, is under investigation after threatening to rape a young woman who is a Navy recruit.
The young woman posted a photo of herself on Facebook, captioning it to say she’s proud of how she’s working hard to get in shape for the Navy, and she’s excited to be leaving soon. The photo was shared on the page for her Delayed Entry Program for her fellow Navy recruits.
Nicholas Lord, who is not a current recruit and who has been serving in the Navy since 2008, then commented:
You’ll end up pregnant real soon you fucking wh***. If I could and I knew you, I’d hold you down and rape you.
The next day, Lord gloated about his threat on his Facebook page, updating his status to say he’d been “trolling feminist pages.” In case it needs to be said, the Facebook page for a Navy program is not a “feminist page.” It’s a Navy recruiting page. (x) (x)
I don’t know what the Navy’s punishment system is like, but I hope he gets the worst possible. I hope they investigate his past history in the military, too. If he’s bold enough to outright threaten female recruits, under his own name, on public, Navy-run social media, I seriously doubt he hasn’t harassed and threatened female sailors. He may even have raped them.
Especially given the military’s problem with letting men get away with harassment and rape, they need to severely punish him.
Send it viral, and he will see ramifications.
If you only reblog one thing today I hope it’s this.
"My dog hates having his picture taken." -lawsonj123
This dog is my spirit animal.
MEDICAL MIRACLES: GHOST HEART
If you took a heart and put it in an ingredient commonly found in shampoo, it would slowly wash away the heart until it became a sort of frame.
Inject this heart with millions of stem cells, from a person who needs a heart transplant and place it in a box that will pump all the good stuff into it (oxygen, blood) and it will slowly turn into a healthy heart.
Researchers believe this heart won’t be rejected because it’s made out of the receiver’s own cells!
Doris Taylor, the mastermind behind this has tried it on everything pig hearts, rat hearts, but not human hearts just yet.
Let’s hope for the best, because this is amazing.
found this on fb thought you guys’d like it. original link
oh my god. this is so depressing
also just imagine House reacting to all of these.
“A dog doesn’t care if your rich or poor, clever or dull, smart or dumb. Give him your heart and he’ll give you his.”
This movie brought out so many feels..
I cried so much.
I’m with you Piper.
Doodling the Right Thing
With a few humble doodles, I think Google may have created the most widely-seen, and perhaps the most influential, science communication effort on Earth. Their series of Google search page tributes to female scientists (a few of which I’ve shared above) is a huge win for showcasing the efforts of women in science, which, unless you’ve been living under a very patriarchal rock for the past forever, you know is something the world needs very badly.
It might seem silly to be talking about a picture like this, but we’re dealing with the Times Square billboard of internet graphics here. Every day, 730 million people visit Google.com a total of 17 billion times. Billion. Granted, not all of them see the same Google doodle, as only a small set of them are “global” doodles, but even if just 10% of daily unique visitors see a particular doodle, and just 10% of those people take the time to figure out who/what they’re looking at, that means 7+ million people a day (and that doesn’t even take into account repeated visits). I suspect that’s a low estimate, too, although I base that on nothing except my own optimism.
As an introvert, I’ve done, and do, all of these things…. constantly.
i definitely have introvert tendencies because i do all of these things
Didn’t think anyone else besides me did these.
Doing these things does not make you introverted.
This is ANXIETY.
That meme is called “Anxiety Cat.” Don’t confuse introversion with anxiety, you are likely misdiagnosing yourself.
You can be introverted and have anxiety at the same time, absolutely, but introversion has to do with how your mind re-energizes itself and recuperates. Extraverts are energized by being in groups with other people, introverts are energized by alone time. Many introverts have excellent people skills, and many extraverts are socially awkward. I myself am an introvert but I have always worked customer service and am excellent at chit chat and conversation with strangers. One of my close friends always wants to be surrounded by friends for her mental boost, but she’s awful at dealing with strangers in any situation (I always end up taking over).
TL;DR- The things listed in the meme above are things people with anxiety are likely to do, not introverted people. Introversion is very misunderstood, and so is anxiety, so make sure you understand the difference.
HOW TO SURVIVE A HEART ATTACK WHEN ALONE
Let’s say it’s 6.15pm and you’re going home (alone of course), after an unusually hard day on the job. You’re really tired, upset and frustrated. Suddenly you start experiencing severe pain in your chest that starts to drag out into your arm and up into your jaw. You are only about five miles from the hospital nearest your home. Unfortunately you don’t know if you’ll be able to make it that far. You have been trained in CPR, but the guy that taught the course did not tell you how to perform it on yourself..!!
NOW HOW TO SURVIVE A HEART ATTACK WHEN ALONE…
Since many people are alone when they suffer a heart attack, without help, the person whose heart is beating improperly and who begins to feel faint, has only about 10 seconds left before losing consciousness.
However, these victims can help themselves by coughing repeatedly and very vigorously.
A deep breath should be taken before each cough, and the cough must be deep and prolonged, as when producing sputum from deep inside the chest.
A breath and a cough must be repeated about every two seconds without let-up until help arrives, or until the heart is felt to be beating normally again.
Deep breaths get oxygen into the lungs and coughing movements squeeze the heart and keep the blood circulating.
The squeezing pressure on the heart also helps it regain normal rhythm. In this way, heart attack victims can perhaps buy precious time to get themselves to a phone and dial 911.
Rather than sharing another joke please contribute by broadcasting this which can save a person’s life!
Be prepared and become part of the solution. Get your free next-of-kin notification card today. Click here: https://www.InCaseOfEmergencyCard.com/
HOW WILL I DIE?
"happy with ranch dressing"
Tortured by hugs.
This peaces me.
run over by every member of limp bizkit
I feel bad for the guy named William Smith or Carlos Garcia
Suffocated by my existence
Fellated by life
Sounds about right.
Devoured by my failures
At first I got excited, and then it just got sad
How History Books Will Remember The Government Shut Down: A Masterpost
i never want this post to die
I miss this
Since her death in 1979, the woman who discovered what the universe is made of has not so much as received a memorial plaque. Her newspaper obituaries do not mention her greatest discovery. […] Every high school student knows that Isaac Newton discovered gravity, that Charles Darwin discovered evolution, and that Albert Einstein discovered the relativity of time. But when it comes to the composition of our universe, the textbooks simply say that the most abundant atom in the universe is hydrogen. And no one ever wonders how we know.
Jeremy Knowles, discussing the complete lack of recognition Cecilia Payne gets, even today, for her revolutionary discovery. (via alliterate)
OH WAIT LEMME TELL YOU ABOUT CECILIA PAYNE.
Cecilia Payne’s mother refused to spend money on her college education, so she won a scholarship to Cambridge.
Cecilia Payne completed her studies, but Cambridge wouldn’t give her a degree because she was a woman, so she said fuck that and moved to the United States to work at Harvard.
Cecilia Payne was the first person ever to earn a Ph.D. in astronomy from Radcliffe College, with what Otto Strauve called “the most brilliant Ph.D. thesis ever written in astronomy.”
Not only did Cecilia Payne discover what the universe is made of, she also discovered what the sun is made of (Henry Norris Russell, a fellow astronomer, is usually given credit for discovering that the sun’s composition is different from the Earth’s, but he came to his conclusions four years later than Payne—after telling her not to publish).
Cecilia Payne is the reason we know basically anything about variable stars (stars whose brightness as seen from earth fluctuates). Literally every other study on variable stars is based on her work.
Cecilia Payne was the first woman to be promoted to full professor from within Harvard, and is often credited with breaking the glass ceiling for women in the Harvard science department and in astronomy, as well as inspiring entire generations of women to take up science.
Cecilia Payne is awesome and everyone should know her.
always reblog because you know women